/
/
Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
A subscription to JoVE is required to view this content. Sign in or start your free trial.
6,455 Views
•
12:50 min
•
September 15, 2017
DOI:
Summary
Automatically generated
Vascular endothelium tightly controls leukocyte recruitment. Inadequate leukocyte extravasation contributes to human inflammatory diseases. Therefore, searching for novel regulatory elements of endothelial activation is necessary to design improved therapies for inflammatory disorders. Here, we describe a comprehensive methodology to characterize novel endothelial regulators that can modify leukocyte trafficking during inflammation.
Read Article
Cite this Article
Higueras, M. Á., Jiménez-García, L., Herranz, S., Hortelano, S., Luque, A. Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response. J. Vis. Exp. (127), e55824, doi:10.3791/55824 (2017).
Copy