This content is Free Access.
10,062 Views
•
00:05 min
•
August 25, 2020
DOI:
Summary
Automatically generated
This study describes an invasive procedure for the induction of accelerated atherosclerosis in mice. In comparison to other methods using electric- or cryo-induced injury, mechanical-induced injury mimics the human condition of restenosis after revascularization therapies and is ideal for the study of the molecular mechanisms involved.
Read Article
Cite this Article
Curaj, A., Zhoujun, W., Staudt, M., Liehn, E. A. Induction of Accelerated Atherosclerosis in Mice: The "Wire-Injury" Model. J. Vis. Exp. (162), e54571, doi:10.3791/54571 (2020).
Copy