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免疫学と感染
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In Vivo Bioluminescent Model of Chagas Disease for Drug Evaluation
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Author Spotlight: Real-Time Monitoring of Parasite Burden and Host Response
JoVE Journal
免疫学と感染
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JoVE Journal 免疫学と感染
Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies

Author Spotlight: Real-Time Monitoring of Parasite Burden and Host Response

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01:51 min

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May 31, 2024

DOI:

10.3791/66740-v

DOI:
10.3791/66740-v

•

01:51 min
May 31, 2024

•

36 Views
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1Departamento de Microbiologia, Instituto de Ciências Biomédicas (ICB),Universidade de São Paulo, 2Drugs for Neglected Diseases initiative (DNDi) Latin America, 3Programa de Pós-Graduação em Microbiologia e Imunologia,Universidade Federal de São Paulo, 4Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas,Universidade de São Paulo

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In Vivo Bioluminescence ImagingChagas DiseaseMouse ModelDrug Efficacy StudiesTrypanosoma CruziLuciferaseNeglected Tropical DiseasesParasite BiologyDisease PathogenesisResearch And DevelopmentIn Vitro And In Vivo Study ModelsQuality Control ProceduresData Acquisition And Analysis

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da Silva, A. C., Kratz, J. M., Morgado, P. G. M., Freitas-Junior, L. H., Moraes, C. B. Demystifying In Vivo Bioluminescence Imaging of a Chagas Disease Mouse Model for Drug Efficacy Studies. J. Vis. Exp. (207), e66740, doi:10.3791/66740 (2024).

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