A protocol for mapping the three-dimensional genome organization with nucleosome resolution using the genome-wide chromosome conformation capture method Micro-C-XL is presented here.
Metelova, M., Jensen, R. R., Krietenstein, N. Mapping Mammalian 3D Genome Interactions with Micro-C-XL. J. Vis. Exp. (201), e64579, doi:10.3791/64579 (2023).