The protocol aims to provide methods for encephalomyosynangiosis-grafting of a vascular temporalis muscle flap on the pial surface of ischemic brain tissue-for the treatment of non-moyamoya acute ischemic stroke. The approach's efficacy in increasing angiogenesis is evaluated using a transient middle cerebral artery occlusion model in mice.
Paro, M. R., Gamiotea Turro, D., Mcgonnigle, M., Bulsara, K. R., Verma, R. A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice. J. Vis. Exp. (184), e63951, doi:10.3791/63951 (2022).