This contribution describes how to set up protein crystallization on crystal-on-crystal devices and how to perform automated serial data collection at room temperature using the on-chip crystallization platform.
Biju, L. M., Wang, C., Kang, W., Tom, I. P., Kumarapperuma, I., Yang, X., Ren, Z. On-Chip Crystallization and Large-Scale Serial Diffraction at Room Temperature. J. Vis. Exp. (181), e63022, doi:10.3791/63022 (2022).