This article describes a protocol for the manipulation of molecular targets in the cerebral cortex using adeno-associated viruses and for monitoring the effects of this manipulation during wakefulness and sleep using electrocorticographic recordings.
Dufort-Gervais, J., Havekes, R., Mongrain, V. Electrocorticographic Recording of Cerebral Cortex Areas Manipulated Using an Adeno-Associated Virus Targeting Cofilin in Mice. J. Vis. Exp. (168), e61976, doi:10.3791/61976 (2021).