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In vivo Evaluation of Mucociliary Clearance in Mice
JoVE Journal
生物学
This content is Free Access.
JoVE Journal 生物学
In vivo Evaluation of Mucociliary Clearance in Mice

In vivo Evaluation of Mucociliary Clearance in Mice

DOI:

06:35 min

December 18, 2020

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  • 00:04Introduction
  • 00:39Mouse Intubation and Instillation
  • 02:06Single Photon Emission Computed Tomography and Computed Tomography (SPECT/CT) Imaging
  • 03:10Analysis
  • 04:48Results: Representative Mouse Mucociliary Clearance (MCC) Evaluation
  • 05:56Conclusion

概要

自動翻訳

In this publication, we describe protocols for assessing airway mucociliary clearance (MCC) in mice in vivo utilizing dual-modality radionuclide imaging. This protocol is designed for a single photon emission computed tomography (SPECT) and computed tomography (CT) acquisition protocol using mouse whole body (MWB) collimators in a dual SPECT/CT system.

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