This paper presents methods for growing cardiac myocytes with different shapes, which represent different pathologies, and sorting these adherent cardiac myocytes based on their morphology at a single cell level. The proposed platform provides a novel approach to high throughput and drug screening for different types of heart failure.
Haftbaradaran Esfahani, P., Knöll, R. An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level. J. Vis. Exp. (165), e61577, doi:10.3791/61577 (2020).