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Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
JoVE Journal
免疫学と感染
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JoVE Journal 免疫学と感染
Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

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10:03 min

November 05, 2019

DOI:

10:03 min
November 05, 2019

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概要

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Here, we describe a method to induce meningococcal meningitis through an intracisternal route of infection in adult mice. We present a step by step protocol of meningococcal infection from the preparation of inoculum to the intracisternal infection; then record the animal survival and evaluate the bacterial loads in murine tissues.

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