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Organidi neurali umani per lo studio del cancro al cervello e delle malattie neurodegenerative
1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine,University of Geneva, 2Department of Pathology and Immunology, University Medical Center,University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring,Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO,University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics,Geneva University Hospitals
章
- 00:04標題
- 00:52hESC-derived Neural Organoids for Glioblastoma Multiforme Studies
- 04:39hESC-derived Dopaminergic Organoids for Parkinson s Disease Studies
- 08:12Results: Generation of Dopaminergic Neural Organoid and Electrophysiological and Morphological Analysis
- 09:14Conclusion
Questo studio introduce e descrive protocolli per derivare due organoidi neurali umani specifici come un modello rilevante e accurato per lo studio 1) lo sviluppo del glioblastoma umano all'interno di organoidi neurali umani esclusivamente negli esseri umani e 2) neuronergico differenziazione generando un organoide tridimensionale.
