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Organoides neuronales humanos para el estudio del cáncer cerebral y las enfermedades neurodegenerativas
1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine,University of Geneva, 2Department of Pathology and Immunology, University Medical Center,University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring,Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO,University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics,Geneva University Hospitals
章
- 00:04標題
- 00:52hESC-derived Neural Organoids for Glioblastoma Multiforme Studies
- 04:39hESC-derived Dopaminergic Organoids for Parkinson s Disease Studies
- 08:12Results: Generation of Dopaminergic Neural Organoid and Electrophysiological and Morphological Analysis
- 09:14Conclusion
Este estudio introduce y describe protocolos para derivar dos organoides neuronales humanos específicos como un modelo relevante y preciso para el estudio de 1) desarrollo de glioblastoma humano dentro de organoides neuronales humanos exclusivamente en humanos y 2) neurona dopaminérgica diferenciación que genera un organoide tridimensional.
