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Murine Myocardial Infarction Model using Permanent Ligation of Left Anterior Descending Coronary Artery
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08:38 min
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August 16, 2019
DOI:
1Service of Adult Intensive Care Medicine, Department of Interdisciplinary Centers and Logistics, Lausanne University Hospital and Faculty of Biology and Medicine,Lausanne University, 2Service of Thoracic Surgery, Department of Surgery and Anesthesiology Services, Lausanne University Hospital and Faculty of Biology and Medicine,Lausanne University
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Herein we describe a surgical procedure showing how to achieve permanent ligation of the left-anterior descending coronary artery in mice. This model is of high relevance to investigate the pathophysiology of myocardial infarction and the concomitant biological processes.
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Lugrin, J., Parapanov, R., Krueger, T., Liaudet, L. Murine Myocardial Infarction Model using Permanent Ligation of Left Anterior Descending Coronary Artery. J. Vis. Exp. (150), e59591, doi:10.3791/59591 (2019).
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