This paper describes a protocol for cognitive assessments for genetic models of the Alzheimer's disease using the IntelliCage system, which is a high throughput automated behavioral monitoring system with operant conditioning.
Masuda, A., Kobayashi, Y., Itohara, S. Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage. J. Vis. Exp. (138), e58009, doi:10.3791/58009 (2018).