This protocol describes a method for investigating the possibility of metamemory, or memory awareness, in rodents. The odor-based delayed-matching-to-sample paradigm is a novel, ecologically-relevant behavioral test useful for determining the extent to which rodents can adaptively respond based on cognitively monitoring the strength of their memory states.
Lee, K. A., Preston, A. J., Wise, T. B., Templer, V. L. Testing for Metacognitive Responding Using an Odor-based Delayed Match-to-Sample Test in Rats. J. Vis. Exp. (136), e57489, doi:10.3791/57489 (2018).