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DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering
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November 09, 2017
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This protocol describes the synthesis of magnetic particles and evaluation of their DNA-binding properties via dynamic and electrophoretic light scattering. This method focuses on monitoring changes in particle size, their polydispersity and zeta potential of particle surface which play major role in binding of materials such as DNA.
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Haddad, Y., Dostalova, S., Kudr, J., Zitka, O., Heger, Z., Adam, V. DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering. J. Vis. Exp. (129), e56815, doi:10.3791/56815 (2017).
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