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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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JoVE Journal 免疫学と感染
Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

18,194 Views

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10:04 min

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September 05, 2017

DOI:

10.3791/56375-v

DOI:
10.3791/56375-v

•

10:04 min
September 05, 2017

•

3 Views
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1Department of Microbiology and Molecular Genetics,University of Pittsburgh School of Medicine, 2Department of Pediatrics, Children’s Hospital of Pittsburgh,University of Pittsburgh Medical Center

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Here, we present a protocol to describe the analysis of 18F-FDG PET/CT imaging in non-human primates that have been infected with M. tuberculosis to study disease process, drug treatment, and disease reactivation.

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Keyword Extraction:PET/CT ImagingMycobacterium TuberculosisNon-human PrimatesTuberculosisLesion MeasurementLung AvidityCT PulmonaryRegion Of InterestWindow LevelWindow Width

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White, A. G., Maiello, P., Coleman, M. T., Tomko, J. A., Frye, L. J., Scanga, C. A., Lin, P. L., Flynn, J. L. Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates. J. Vis. Exp. (127), e56375, doi:10.3791/56375 (2017).

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