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激光内在人肺组织中的新型细菌特异探针的光学筛选
JoVE Journal
免疫学と感染
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JoVE Journal 免疫学と感染
Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy
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激光内在人肺组织中的新型细菌特异探针的光学筛选

7,290 Views

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09:24 min

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November 29, 2017

DOI:

10.3791/56284-v

DOI:
10.3791/56284-v

•

09:24 min
November 29, 2017

•

3 Views
, , , ,
1EPSRC Proteus Hub, MRC Centre of Inflammation Research, Queen’s Medical Research Institute,University of Edinburgh, 2School of Chemistry, EaStChem,University of Edinburgh

概要

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这项技术描述了一个有效的筛选过程, 以评估细菌特异性光学成像剂在前体内人肺组织, 通过纤维共聚焦荧光显微镜快速鉴定小分子化学具有可翻译潜力的候选者。

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Cite this Article

Mills, B., Akram, A. R., Scholefield, E., Bradley, M., Dhaliwal, K. Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy. J. Vis. Exp. (129), e56284, doi:10.3791/56284 (2017).

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