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Nanosponge Tunability in Size and Crosslinking Density
章
- 00:05標題
- 00:53Synthesis and Characterization of VL-co-AVL
- 02:56Post-polymerization Epoxidation to Produce Epoxy-valerolactone (EVL) Copolymer Units
- 05:15Nanosponge Synthesis and Characterization
- 07:37TEM Imaging of Nanosponge Morphology and Size
- 08:58Results: Analysis of Nanosponge Trends
- 10:09Conclusion
This article describes a process for tuning the size and crosslinking density of covalently crosslinked nanoparticles from linear polyesters containing pendant functionality. By tailoring synthesis parameters (polymer molecular weight, pendant functionality incorporation, and crosslinker equivalents), a desired nanoparticle size and crosslinking density can be achieved for drug delivery applications.
