We present a behavior recording setup and protocol that enables automated analysis of the nematode, Caenorhabditis elegans' preference for soluble compounds in a population-based assay. This article describes the construction of a behavior chamber, the behavioral assay protocol, and video analysis software usage.
Chai, C. M., Cronin, C. J., Sternberg, P. W. Automated Analysis of a Nematode Population-based Chemosensory Preference Assay. J. Vis. Exp. (125), e55963, doi:10.3791/55963 (2017).