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Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
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February 05, 2018
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A modular approach to the synthesis of N-glycans for attachment to an aluminum oxide-coated glass slide (ACG slide) as a glycan microarray has been developed and its use for the profiling of an HIV broadly neutralizing antibody has been demonstrated.
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Shivatare, S. S., Shivatare, V. S., Wu, C., Wong, C. Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling. J. Vis. Exp. (132), e55855, doi:10.3791/55855 (2018).
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