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Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
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JoVE Journal 神経科学
Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

10,743 Views

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08:11 min

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November 14, 2016

DOI:

10.3791/54616-v

DOI:
10.3791/54616-v

•

08:11 min
November 14, 2016

•

4 Views
, ,
1Department of Neurology,Geisel School of Medicine at Dartmouth

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An optimized testing protocol is presented in this paper for the Rotarod performance test, used for measuring progressive neurological disability in TMEV-infected mice.

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Mouse ModelMultiple SclerosisProgressive Neurological DisabilityRotarod TestTheilers VirusMotor FunctionBalance CoordinationAcclimationTraining ProtocolTime To FallTrials

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Gilli, F., Royce, D. B., Pachner, A. R. Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis. J. Vis. Exp. (117), e54616, doi:10.3791/54616 (2016).

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