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Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite
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February 16, 2016
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概要
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Exposure to teratogens may cause birth defects. Zebrafish are useful for determining the teratogenic potential of chemicals. We demonstrate the utility of zebrafish by exposing embryos to various levels of nitrite and also at different times of exposure. We show that nitrite can be toxic and cause severe developmental defects.
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Keshari, V., Adeeb, B., Simmons, A. E., Simmons, T. W., Diep, C. Q. Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite. J. Vis. Exp. (108), e53615, doi:10.3791/53615 (2016).
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