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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
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October 05, 2015
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Human tuberculosis infection is a complex process, which is difficult to model in vitro. Here we describe a novel 3D human lung tissue model that recapitulates the dynamics that occur during infection, including the migration of immune cells and early granuloma formation in a physiological environment.
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Braian, C., Svensson, M., Brighenti, S., Lerm, M., Parasa, V. R. A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection. J. Vis. Exp. (104), e53084, doi:10.3791/53084 (2015).
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