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Intravenous Injections in Neonatal Mice
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JoVE Journal 生物学
Intravenous Injections in Neonatal Mice

Intravenous Injections in Neonatal Mice

DOI:
10.3791/52037-v

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05:17 min

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November 11, 2014

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, ,
1神経科学科,Ohio State University, 2Center for Gene Therapy, Nationwide Children’s Hospital Research Institute,Ohio State University

章

  • 00:05標題
  • 00:52Preparation and Injection Procedure
  • 03:06Post-Injection
  • 04:04Results: GFP Expression after Neonate Intravenous Injection
  • 04:55Conclusion

概要

自動翻訳

自動翻訳

Animal models of pediatric disease can experience early onset and aggressive disease progression. Clinically relevant therapy delivery to young mouse models can be technically difficult. This protocol describes a non-invasive intravenous injection method for newborn mice within the first two postnatal days of life.

タグ

Intravenous InjectionNeonatal MiceTemporal VeinAdeno-associated VirusAAVTransgene ExpressionTherapeutic DeliveryMouse ModelsEarly Onset Disease

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