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相干反斯托克斯拉曼散射（CARS）显微可视化药片剂溶出过程中
JoVE Journal
工学
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JoVE Journal 工学
Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution
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相干反斯托克斯拉曼散射（CARS）显微可视化药片剂溶出过程中

17,751 Views

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09:59 min

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July 04, 2014

DOI:

10.3791/51847-v

DOI:
10.3791/51847-v

•

09:59 min
July 04, 2014

•

3 Views
, , , ,
1Optical Sciences Group, MESA+ Institute,University of Twente, 2Institute of Pharmaceutics and Biopharmaceutics,Heinrich-Heine University, 3Division of Pharmaceutical Technology, Faculty of Pharmacy,University of Helsinki

概要

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相干反斯托克斯拉曼散射（CARS）显微术是结合本征流通过溶解的设置，以允许在原位和药物片剂进行溶出度的表面的实时可视化。使用这种定制的设置，因此能够使用内联紫外吸收光谱记录药物溶出曲线相关CARS视频。

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Cite this Article

Fussell, A. L., Kleinebudde, P., Herek, J., Strachan, C. J., Offerhaus, H. L. Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution. J. Vis. Exp. (89), e51847, doi:10.3791/51847 (2014).

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