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Massively Parallel Reporter Assays in Cultured Mammalian Cells
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August 17, 2014
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The genetic reporter assay is a well-established and powerful tool for dissecting the relationship between DNA sequences and their gene regulatory activities. Coupling candidate regulatory elements to reporter genes that carry identifying sequence tags enables massive parallelization of these assays.
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Melnikov, A., Zhang, X., Rogov, P., Wang, L., Mikkelsen, T. S. Massively Parallel Reporter Assays in Cultured Mammalian Cells. J. Vis. Exp. (90), e51719, doi:10.3791/51719 (2014).
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