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A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury
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January 05, 2015
DOI:
1Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman and Campbell Brain and Spine,Indiana University School of Medicine, 2Medical Neuroscience Graduate Program,Indiana University School of Medicine, 3解剖・細胞生物学科,Indiana University School of Medicine, 4Norton Neuroscience Institute,Norton Healthcare
概要
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Vertebral stabilization is necessary for minimizing variability, and for producing consistent experimental spinal cord injuries. Using a customized stabilizing apparatus in conjunction with the NYU/MASCIS impactor device, we have demonstrated here the proper equipment and procedure for generating reproducible hemi-contusive cervical (C5) spinal cord injuries in adult rats.
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Walker, M. J., Walker, C. L., Zhang, Y. P., Shields, L. B. E., Shields, C. B., Xu, X. A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury. J. Vis. Exp. (95), e50149, doi:10.3791/50149 (2015).
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