ジャーナル
/
免疫学と感染
/
Multi-target Parallel Processing Aanpak voor Gene-to-structuur bepalen van de Influenza Polymerase PB2 Subunit
JoVE Journal
免疫学と感染
This content is Free Access.
JoVE Journal 免疫学と感染
Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
Please note that all translations are automatically generated. Click here for the English version.

Multi-target Parallel Processing Aanpak voor Gene-to-structuur bepalen van de Influenza Polymerase PB2 Subunit

12,908 Views

•

22:10 min

•

June 28, 2013

DOI:

10.3791/4225-v

DOI:
10.3791/4225-v

•

22:10 min
June 28, 2013

•

1 Views
, , , , , , , , , ,
1Protein Crystallization Lab,Emerald Bio, 2Molecular Biology Lab,Emerald Bio, 3Scientific Sales Representative,Emerald Bio, 4Group Leader II,Emerald Bio, 5Group Leader I,Emerald Bio, 6Chair of Advisory Board,Emerald Bio, 7Director of Multi-Target Services,Emerald Bio, 8Senior Project Leader,Emerald Bio, 9Project Leader II & SSGCID Site Manager,Emerald Bio

概要

Automatically generated

Structure-based drug design speelt een belangrijke rol in de ontwikkeling van geneesmiddelen. Nastreven van meerdere doelen tegelijkertijd verhoogt de kans op succes voor lood ontdekking. Het volgende artikel belicht hoe de Seattle Structural Genomics Centrum Infectieziektebestrijding maakt gebruik van een multi-target benadering voor gen-tot-structuur bepaling van de PB2 influenza A subunit.

Explore More Videos

Multi-targetParallel ProcessingGene-to-structure DeterminationInfluenza Polymerase PB2 SubunitPandemic OutbreaksInfluenza Virus InfectionPoint MutationsVirulence FactorAntiviral Drug TargetStructural Genomics ProgramNational Institute Of Allergy And Infectious Disease (NIAID)Emerald BioSeattle Structural Genomics Center For Infectious Disease (SSGCID)Three-dimensional Protein StructuresNIAID Category A-C PathogensStructure-based Drug DesignDrug Development

Read Article

Cite this Article

Armour, B. L., Barnes, S. R., Moen, S. O., Smith, E., Raymond, A. C., Fairman, J. W., Stewart, L. J., Staker, B. L., Begley, D. W., Edwards, T. E., Lorimer, D. D. Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit. J. Vis. Exp. (76), e4225, doi:10.3791/4225 (2013).

Download .ris file

Copy

Share Video

.

Copy