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Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
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August 24, 2012
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Conditioned fear can be diminished through an inhibitory process called extinction, but can resurface under conditions such as the passage of time or exposure to stress. Our protocol presents a novel way of preventing fear recovery by introducing extinction during the reconsolidation window (the re-storage phase of a reactivated memory).
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Extinction TrainingReconsolidation WindowFear PreventionFear RecoveryPavlovian Fear-conditioning ParadigmsConditioned StimulusUnconditioned StimulusConditioned ResponseExtinction TrainingInhibitory LearningFear MemorySpontaneous Recovery Of FearStress-induced FearContextual Fear ResurfacingEmotional Memory ModificationMemory Reactivation
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Schiller, D., Raio, C. M., Phelps, E. A. Extinction Training During the Reconsolidation Window Prevents Recovery of Fear. J. Vis. Exp. (66), e3893, doi:10.3791/3893 (2012).
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