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Parasite Induced Genetisch Gedreven Auto Chagas hart-en vaatziekten in de Chicken Model
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July 29, 2012
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概要
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De inenting van<em> Trypanosoma cruzi</em> In vruchtbare eieren voor incubatie maakt de parasiet kDNA integratie minicircle in cellen van embryo's genoom. Kruisen toont de verticale verplaatsing van de mutaties nakomelingen. De kDNA integreert in coderende gebieden op verschillende chromosomen en de kippen sterven met een inflammatoire auto-hart-en vaatziekten.
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Teixeira, A. R. L., Nitz, N., Bernal, F. M., Hecht, M. M. Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model. J. Vis. Exp. (65), e3716, doi:10.3791/3716 (2012).
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