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Induction of Myocardial Infarction in Adult Zebrafish Using Cryoinjury
JoVE Journal
医学
This content is Free Access.
JoVE Journal 医学
Induction of Myocardial Infarction in Adult Zebrafish Using Cryoinjury

Induction of Myocardial Infarction in Adult Zebrafish Using Cryoinjury

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11:12 min

April 18, 2012

DOI:

11:12 min
April 18, 2012

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概要

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Zebrafish represents a valuable model to study the mechanisms of heart regeneration in vertebrates. Here, we present a protocol for induction of a heart infarct in adult zebrafish using cryoinjury. This method results in massive cell death within 20% of the ventricular wall, similar to that observed in mammalian infarcts.

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