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Neural Tube Closure in Mouse Whole Embryo Culture
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October 21, 2011
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A method allowing for direct pharmacological manipulation of mouse embryos during neurulation that bypasses maternal metabolism is described. The technique can be adapted to study different aspects of neurulation by varying the time point and pharmacological agent.
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Gray, J., Ross, M. E. Neural Tube Closure in Mouse Whole Embryo Culture. J. Vis. Exp. (56), e3132, doi:10.3791/3132 (2011).
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