ジャーナル
/
生物学
/
Transverse Aortic Constriction in Mice
JoVE Journal
生物学
このコンテンツを視聴するには、JoVE 購読が必要です。  サインイン又は無料トライアルを申し込む。
JoVE Journal 生物学
Transverse Aortic Constriction in Mice

Transverse Aortic Constriction in Mice

DOI:
10.3791/1729-v

•

08:25 min

•

April 21, 2010

•

, ,
1Department of Molecular Physiology and Biophysics,Baylor College of Medicine (BCM), 2The Margaret M. and Albert B. Alkek Department of Medicine,Baylor College of Medicine (BCM)

章

  • 00:00標題
  • 00:42Introduction
  • 01:10Preparing the Operating Field
  • 02:02Preparing and Intubation of Mice
  • 03:25Ligation of the Transverse Aorta
  • 06:31Confirmation of Successful Ligation of the Transverse Aorta
  • 07:32Results of a Successful Transverse Aortic Constriction
  • 08:02Conclusion

概要

自動翻訳

自動翻訳

Transverse aortic constriction (TAC) in the mouse is a commonly used experimental model to study mechanisms underlying cardiac hypertrophy and heart failure development. Here, we describe procedures to constrict the aorta to create a reproducible degree of cardiac hypertrophy in mice.

タグ

Transverse Aortic ConstrictionTACPressure OverloadCardiac HypertrophyHeart FailureMurine TAC ModelCardiovascular DiseasesSignaling ProcessesLeft Anterior Descending Coronary Artery OcclusionReproducible ModelGradual Time CourseSurgical ProcedureHigh Frequency Doppler ProbeBlood Flow VelocitiesLeft Ventricular Hypertrophy

Article

Embed

プレイリスト追加

Usage Statistics

関連ビデオ

Heterotopic Heart Transplantation in Mice

Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase

Aortic Ring Assay

Isolation and Primary Culture of Mouse Aortic Endothelial Cells

Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice

Isolation and Culture of Primary Aortic Endothelial Cells from Miniature Pigs

Transverse Fracture of the Mouse Femur with Stabilizing Pin

Isolation of Primary Patient-specific Aortic Smooth Muscle Cells and Semiquantitative Real-time Contraction Measurements In Vitro

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

Read Article