2.18:

Brain Imaging

JoVE Core
Introduction to Psychology
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JoVE Core Introduction to Psychology
Brain Imaging

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01:14 min

October 24, 2024

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.

These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

CT scans, employing X-ray technology, create detailed three-dimensional images of the brain. This method is particularly valuable in emergency settings for its speed and efficiency in detecting hemorrhages, tumors, or other brain abnormalities. By providing a structural overview, CT scans serve as a fundamental tool in medical science for assessing the severity and location of brain lesions.

PET scans offer a dynamic perspective by using a mildly radioactive tracer to identify metabolically active areas of the brain. These regions demonstrate increased blood demand during various activities or in response to certain stimuli, making PET an essential method for studying brain functions like memory and cognition. This ability to visualize active brain parts during specific tasks helps in understanding the metabolic changes associated with various brain disorders.

MRI uses a powerful magnetic field combined with radio waves to elicit detailed responses from brain tissues. This modality is crucial for providing high-resolution images vital for diagnosing and understanding a wide range of normal and pathological brain conditions. Unlike CT scans, MRI does not use ionizing radiation, which makes it a safer option for repeated use, particularly in vulnerable populations such as children and pregnant women.

fMRI builds upon the technology used in MRI to measure and map the brain's activity. By monitoring changes in blood flow and oxygen levels, fMRI can correlate these physical changes to neural activity. This technique enables researchers to observe the brain's functional anatomy and offers a real-time view of brain processes as individuals engage in tasks or respond to various stimuli. This application is crucial for understanding the neural basis of behaviors and enhancing cognitive neuroscience research.

TMS uses magnetic fields to modulate the electrical activity of specific brain areas, offering a non-invasive method to alter neural function. This technology is particularly effective in mapping functional regions of the brain, assessing the connectivity and functionality of neural circuits, and providing therapeutic interventions in psychiatric and neurological disorders. The ability to directly influence brain function with TMS opens new avenues for treating conditions such as depression and schizophrenia, where traditional therapies have been insufficient.