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21.1:

An Overview of the Endocrine System

JoVE Core
Anatomy and Physiology
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JoVE Core Anatomy and Physiology
An Overview of the Endocrine System

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The endocrine system is made of glands and organs that produce and secrete hormones.

Hormones are chemical signals that act as messengers between neighboring cells and distant sites in the body.

Many hormones are secreted into the extracellular fluid and move through the circulatory system to reach their target. However, they can only affect cells with receptors for a given hormone.

The endocrine system regulates many biological processes through these signals, including metabolism, reproduction, and development.

The endocrine and nervous systems mediate intercellular communication and work together to maintain homeostasis, but each has a specific time frame and means of relaying information.

Nerve impulses travel quickly through the body through electrical signals and the release of neurotransmitters but stop their effect immediately after removing a stimulus.

A person will quickly notice a hot object but will no longer feel the heat after removing their hand.

Some hormones can trigger rapid responses, like adrenaline, in fight-or-flight situations. Others initiate long-term signaling, such as reproductive hormones, that have an effect even after their removal.

21.1:

An Overview of the Endocrine System

The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.

The endocrine system collaborates with the nervous system to uphold homeostasis, regulating fundamental biological processes like metabolism, reproduction, and development. Although both systems engage in intercellular communication, they differ in their temporal dynamics and modes of information transmission. Nerve impulses rapidly propagate through the body via electrical signals and neurotransmitter release. Still, their effects promptly cease upon stimulus removal, as exemplified by the sensation of heat dissipating after removing a hand from a hot object.

Conversely, hormones exhibit diverse temporal patterns, with some triggering rapid responses, like the immediate surge of adrenaline in fight-or-flight situations. In contrast, others, such as reproductive hormones, instigate prolonged signaling, exerting influence even after removal. This intricate interplay between the endocrine and nervous systems underscores the sophistication of the body's regulatory mechanisms, ensuring adaptability and responsiveness to various physiological challenges.