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6.10:

Osmosis

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Anatomy and Physiology
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JoVE Core Anatomy and Physiology
Osmosis

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Osmosis is the movement of a solvent, such as water, from a lower to a higher solute concentration across a semipermeable membrane.

The number of solute particles per liter of a solution is called osmolarity. It determines the osmotic pressure— the minimum pressure required to prevent osmosis.

In a cell, if the osmolarity inside is higher than outside, water continues to move into the cell until both sides attain equal solute concentration and osmotic pressure becomes zero.

Usually, the polar water molecules diffuse slowly across the lipid bilayer. For rapid osmosis, water-specific channel proteins called aquaporins selectively transport water molecules according to the osmotic gradient.

In kidneys, the renal tubules reabsorb water and solutes from the plasma filtrate via osmosis and return them to the bloodstream.

The filtrate from the tubule lumen that enters tubule wall cells contain high ion concentrations.

As the ions are actively transported out of the tubule cells, their osmolarity within the cell becomes lower than in the surrounding capillaries. To balance, water molecules move through the aquaporins into the bloodstream.

6.10:

Osmosis

Osmosis is the movement of free water molecules through a semipermeable membrane.  The water's concentration gradient across the membrane is inversely proportional to the solutes' concentration. Whereas diffusion transports material across membranes and within cells, osmosis transports only water across a membrane, and the membrane limits the diffusion of solutes in the water. Osmosis is a special case of diffusion.

Water, like other substances, moves from a high concentration of free water molecules to a low concentration of free water molecules. Imagine a beaker with a semipermeable membrane separating the two sides or halves. On both sides of the membrane, the water level is the same, but there are different concentrations on each side of a dissolved substance, or solute, that cannot cross the membrane.

A principle of diffusion is that the molecules move and will spread evenly throughout the medium if they can. However, only the material capable of getting through the membrane will diffuse through it. In this example, the solute cannot diffuse through the membrane, but the water can. Water has a concentration gradient in this system. Therefore, water will diffuse down its concentration gradient, crossing the membrane to the side where it is less concentrated. This diffusion of water through the membrane will continue until the concentration gradient of water goes to zero. Osmosis constantly occurs in living systems.

This text is adapted from Openstax, Concepts of Biology, Section 3.5 Passive Transport.