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免疫学と感染
In Vivo Bioluminescent Model of Chagas Disease for Drug Evaluation

In Vivo Bioluminescent Model of Chagas Disease for Drug Evaluation

May 31, 2024

Author Spotlight: Real-Time Monitoring of Parasite Burden and Host Response

01:51 min
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585 Views

In Vivo Imaging of a Bioluminescent Mouse Model of Trypanosoma cruzi Infection for Drug Efficacy Studies

01:22 min
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35 Views

Data Analysis of a Bioluminescent Mouse Model of Trypanosoma cruzi Infection for Drug Efficacy Studies

04:54 min
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86 Views
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1Departamento de Microbiologia, Instituto de Ciências Biomédicas (ICB),Universidade de São Paulo, 2Drugs for Neglected Diseases initiative (DNDi) Latin America, 3Programa de Pós-Graduação em Microbiologia e Imunologia,Universidade Federal de São Paulo, 4Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas,Universidade de São Paulo

概要

The protocol provided here describes the detailed steps to perform drug efficacy studies in a bioluminescent model of Trypanosoma cruzi infection, with a focus on data acquisition, analysis, and interpretation. Troubleshooting and quality control procedures to minimize technical issues are also provided.

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