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神経科学
Establishing the Mouse Model for Trigeminal Neuropathic Pain

Establishing the Mouse Model for Trigeminal Neuropathic Pain

March 08, 2024

Author Spotlight: Utilizing Infraorbital Nerve Ligation in Mice for Investigating Trigeminal Neuropathic Pain and Treatment Strategies

01:14 min
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279 Views

Infraorbital Nerve Surgery in Mouse

01:45 min
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46 Views

Behavioral Testing and Mechanical Stimulation Assessment in Distal Infraorbital Nerve Chronic Constriction Injured Mouse

02:47 min
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39 Views
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1Antwerp Surgical Training, Anatomy and Research Centre, Algology (pain research),University of Antwerp, 2Multidisciplinary Pain Center,Antwerp University Hospital

概要

Chronic constriction injury of the distal infraorbital nerve in mice induces changes in spontaneous behavior (increased face grooming activity) and nocifensive behavior in response to tactile stimulation (hyperresponsiveness to von Frey hair stimulation) that are signs of ongoing pain and allodynia and serves as a model for trigeminal neuropathic pain.

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