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Subdural Soft Electrocorticography (ECoG) Array Implantation and Long-Term Cortical Recording in Minipigs
JoVE Journal
Bioingegneria
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JoVE Journal Bioingegneria
Subdural Soft Electrocorticography (ECoG) Array Implantation and Long-Term Cortical Recording in Minipigs

Subdural Soft Electrocorticography (ECoG) Array Implantation and Long-Term Cortical Recording in Minipigs

DOI:
10.3791/64997-v

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08:30 min

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March 31, 2023

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, ,
1Laboratory for Soft Bioelectronic Interfaces, Neuro-X Institute,Ecole Polytechnique Fédérale de Lausanne

Capitoli

  • 00:04Introduction
  • 01:06Craniotomy and Durotomy
  • 02:49Implantation of Soft Electrocorticography (ECoG) Arrays
  • 05:10Recording Awake Signals from the Brain
  • 05:33Results: Cortical Recordings and Analysis of Brain After Electrodes Implantation
  • 07:33Conclusion

Summary

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Here, we present a method for the long-term performance and safety assessment of soft subdural electrode arrays in a minipig model, describing surgical method and tools, postoperative magnetic resonance imaging, electrophysiology of the auditory cortex, electrochemical properties of the implant, and postmortem immunochemistry.

Tags

Keywords: SubduralElectrocorticographyECoGArrayImplantationMinipisgsBiocompatibilityResolutionSignal QualityNeural MonitoringSensory NeuroprosthesisMotor NeuroprosthesisCortical NetworksFunctional ConnectivitySurgical ApproachCraniotomyDurotomyDura MaterCortical Implant

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