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Immunologia e infezioni
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Screening of β2 Integrin Activation Inhibitors in Human Neutrophils
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Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation
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Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs

Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation

Screening of β2 Integrin Activation Inhibitors in Human Neutrophils

DOI:
10.3791/64401-v

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00:45 min

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February 02, 2024

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, , , ,
1Department of Immunology, School of Medicine,UConn Health, 2Center for Molecular Discovery,University of New Mexico Health Sciences Center, 3Comprehensive Cancer Center,University of New Mexico Health Sciences Center, 4Department of Pathology,University of New Mexico Health Sciences Center, 5Autophagy, Inflammation, & Metabolism (AIM) Center,University of New Mexico

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Flow CytometryHigh-throughput ScreeningIntegrin InhibitorBeta-2 IntegrinNeutrophilAnti-inflammatoryConformational Change AntibodyFMLPGPCR

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Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation

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