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接触超敏反应作为过敏性接触性皮炎的小鼠模型
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Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
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接触超敏反应作为过敏性接触性皮炎的小鼠模型

2,156 Views

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08:25 min

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September 26, 2022

DOI:

10.3791/64329-v

DOI:
10.3791/64329-v

•

08:25 min
September 26, 2022

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15 Views
, , ,
1Department of Clinical Immunology,Wroclaw Medical University, 2Department of Medical Physiology, Chair of Biomedical Sciences, Institute of Physiotherapy, Faculty of Health Sciences,Jagiellonian University Medical College, 3Chair of Biomedical Sciences, Faculty of Health Sciences,Jagiellonian University Medical College

Summary

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接触性超敏反应（CHS）是过敏性接触性皮炎（ACD）的小鼠实验模型。CHS基于通过涂上胸部和腹部的剃须皮肤对反应性半抗原的致敏，随后用稀释的半抗原进行耳朵皮肤激发，引起肿胀反应，以各种方式评估。

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Cite this Article

Zemelka-Wiacek, M., Majewska-Szczepanik, M., Gajdanowicz, P., Szczepanik, M. Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis. J. Vis. Exp. (187), e64329, doi:10.3791/64329 (2022).

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