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肠系膜上动脉闭塞的肠缺血再灌注损伤的啮齿动物模型
JoVE Journal
Medicina
This content is Free Access.
JoVE Journal Medicina
Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
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肠系膜上动脉闭塞的肠缺血再灌注损伤的啮齿动物模型

DOI:
10.3791/64314-v

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06:29 min

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October 20, 2023

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, , ,
1Animal Surgery and Resources Core, National Heart, Lung, and Blood Institute,National Institutes of Health, 2College of Veterinary Medicine,Mississippi State University, 3Division of Veterinary Resources, Office of Research Services,National Institutes of Health

Capitoli

  • 00:00Introduction
  • 00:05Surgical Setup and Animal Preparation
  • 01:29Surgery and Ischemia
  • 03:56Tissue Collection and Processing for Histology
  • 05:47Results: Post-IRI Analysis of Small Intestine

Summary

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Traduzione automatica

我们描述了如何生成啮齿动物肠缺血再灌注损伤 （IRI） 的广泛使用的手术模型。该手术包括闭塞肠系膜上动脉，然后恢复血流。该模型可用于调查兽医和人类医学中肠道 IRI 闭塞原因的研究。

Tags

Rodent ModelIntestinal Ischemia-reperfusion InjurySuperior Mesenteric Artery OcclusionAnesthesiaBuprenorphineHeparinAbdominal IncisionSuperior Mesenteric ArteryIschemiaReperfusion

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