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Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
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Capitoli
- 00:04Introduction
- 00:51Collection of Fresh Fecal Pellets
- 02:02Preparation of Fecal Suspension
- 02:45Administration of Fecal Suspension by Oral Gavage
- 04:24Results: BNP Up-Regulation and LVEF Down-Regulation Mitigation by FMT
- 05:09Conclusion
The interaction of genetic susceptibility, mucosal immunity, and intestinal microecological environment is involved in the pathogenesis of inflammatory bowel disease (IBD). In this study, we applied fecal microbiota transplantation to IL-10 deficient mice and investigated its impact on colonic inflammation and heart function.
