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JoVE Journal Cancer Research

分析EGFR突变型NSCLC患者衍生类器官靶向治疗的敏感性

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分析EGFR突变型NSCLC患者衍生类器官靶向治疗的敏感性

Article DOI: 10.3791/63039-v • 08:52 min • November 22nd, 2021

November 22nd, 2021 •

Dora Barbosa Rabago^1,2,3, Collin M. Blakely^1,2, Franziska Haderk^1,2,3, Trever G. Bivona^1,2,3

¹Department of Medicine, University of California, San Francisco, ²Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, ³Department of Cellular and Molecular Pharmacology, University of California, San Francisco

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该协议描述了NSCLC患者衍生类器官模型中靶向信号传导抑制剂药物敏感性的标准化评估。

Tags

癌症研究，第177期，类器官，肺类器官，PDO，NSCLC，肺癌，奥西替尼，EGFR，靶向抑制剂，耐药性

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