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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

7,366 Views

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07:12 min

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January 21, 2020

DOI:

10.3791/60562-v

DOI:
10.3791/60562-v

•

07:12 min
January 21, 2020

•

2 Views
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1Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University,Key Laboratory of Acupuncture and Neurology of Zhejiang Province, 2Academy of Chinese Medical Sciences,Zhejiang Chinese Medical University

Summary

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Provided here is a protocol that details steps to establish an animal model of chronic post-ischemia pain (CPIP). This is a well-recognized model mimicking human complex regional pain syndrome type-I. Mechanical and thermal hypersensitivities are further evaluated, as well as capsaicin-induced nocifensive behaviors observed in the CPIP rat model.

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Cite this Article

Hu, Q., Zheng, X., Chen, R., Liu, B., Tai, Y., Shao, X., Fang, J., Liu, B. Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats. J. Vis. Exp. (155), e60562, doi:10.3791/60562 (2020).

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