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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
JoVE Journal
Genetica
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JoVE Journal Genetica
Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

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11:34 min

August 09, 2019

DOI:

11:34 min
August 09, 2019

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Summary

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Sequence specificity is critical for gene regulation. Regulatory proteins that recognize specific sequences are important for gene regulation. Defining functional binding sites for such proteins is a challenging biological problem. An iterative approach for identification of a binding site for an RNA-binding protein is described here and is applicable to all RNA-binding proteins.

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