Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Ranjan Dutta; Kedar R. Mahajan; Kunio Nakamura; Daniel Ontaneda; Jacqueline Chen; Christina Volsko; Jessica Dudman; Emilie Christie; Jordon Dunham; Robert J. Fox; Bruce D. Trapp

doi:10.3791/59511

Rivista

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Neuroscienze

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Omfattende obduktions program for personer med multipel sklerose

JoVE Journal
Neuroscienze

This content is Free Access.

JoVE Journal Neuroscienze

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Omfattende obduktions program for personer med multipel sklerose

DOI:

10.3791/59511-v

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09:41 min

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July 19, 2019

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Ranjan Dutta*¹, Kedar R. Mahajan*^1,3, Kunio Nakamura*³, Daniel Ontaneda*², Jacqueline Chen, Christina Volsko, Jessica Dudman, Emilie Christie, Jordon Dunham, Robert J. Fox, Bruce D. Trapp

¹Department of Neurosciences, Lerner Research Institute,Cleveland Clinic, ²Department of Biomedical Engineering, Lerner Research Institute,Cleveland Clinic, ³Mellen Center for Treatment and Research in Multiple Sclerosis, Neurological Institute,Cleveland Clinic

Capitoli

00:04Titolo
01:29Brain Autopsy
03:44Spinal Cord Autopsy
04:47Pathology
07:11Results: Representative Post-mortem Multiple Sclerosis (MS) Brain and Spinal Cord Characterization
08:52Conclusion

Summary

Traduzione automatica

Multipel sklerose er en inflammatorisk demyelinerende sygdom uden helbredelse. Analyse af hjernevæv giver vigtige fingerpeg til at forstå patogenesen af sygdommen. Her diskuterer vi den metode og downstream analyse af MS Brain tissue indsamlet gennem en unik Rapid obduktion program i drift på Cleveland Clinic.