È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
10,002 Views
•
06:57 min
•
June 14, 2019
DOI:
1Department of Pathology, Georges Pompidou European Hospital, Assistance publique – Hôpitaux de Paris (APHP),Paris Descartes University, 2Paris Cardiovascular Research Center (PARCC), Institut national de la santé et de la recherche médicale (Inserm) U970, 3Laboratory of Immunology, Georges Pompidou European Hospital, APHP,Paris Descartes University
Summary
Automatically generated
Human papillomavirus (HPV) RNA chromogenic in situ hybridization is considered to be one of the gold standards for active human papillomavirus infection detection within tumors. It allows the visualization of HPV E6-E7 mRNA expression with localization and semiquantitative evaluation of its signal.
Read Article
Cite this Article
Outh-Gauer, S., Augustin, J., Mandavit, M., Grard, O., Denize, T., Nervo, M., Lépine, C., Rassy, M., Tartour, E., Badoual, C. Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis. J. Vis. Exp. (148), e59422, doi:10.3791/59422 (2019).
Copy