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Spatiotemporally gecontroleerde nucleaire translocatie van gasten in levende cellen gekooide moleculaire lijm als Photoactivatable Tags gebruiken
JoVE Journal
Chimica
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JoVE Journal Chimica
Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags
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Spatiotemporally gecontroleerde nucleaire translocatie van gasten in levende cellen gekooide moleculaire lijm als Photoactivatable Tags gebruiken

10,064 Views

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10:10 min

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January 17, 2019

DOI:

10.3791/58631-v

DOI:
10.3791/58631-v

•

10:10 min
January 17, 2019

•

9 Views
, , ,
1Department of Chemistry and Biotechnology, School of Engineering,University of Tokyo, 2Riken Center for Emergent Matter Science

Summary

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Dit protocol beschrijft licht geactiveerd nucleaire translocatie van gasten in levende cellen met behulp van gekooide moleculaire lijm tags. Deze methode is veelbelovend voor site-selectieve nucleaire-targeting drug delivery.

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Cite this Article

Mogaki, R., Okuro, K., Arisaka, A., Aida, T. Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags. J. Vis. Exp. (143), e58631, doi:10.3791/58631 (2019).

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